The highly controversial and potentially lethal anthrax vaccine may be tested on US children if the federal government gets its way. Although adverse event reports related to the vaccine among adult test subjects have included hospitalization, disability and even death, the U.S. Department of Health and Human Services (DHHS) is exploring the possibility of testing the vaccine on children.
U.S. government doctors once thought it was acceptable to experiment on disabled people and prison inmates, including giving hepatitis to mental patients in Connecticut, squirting a pandemic flu virus up the noses of prisoners in Maryland and injecting cancer cells into chronically ill people at a New York hospital.
Washington state is working to reverse a disturbing trend: the disproportionate use of adult antipsychotic drugs to treat poor kids with mental illness.
A law intended to speed up development of new drugs for US kids has ended up financing clinical trials in poor countries, where the medicines might never become available.
The Supreme Court gave a rare hit to private businesses when it declined to take up a case against pharmaceutical giant Pfizer. The suit alleges the drug company conducted nonconsensual drug testing on over 200 Nigerian children, some of whom died as a result of the tests. The suit was filed under the Alien Tort Statute (ATS) which grants federal judges the ability to hear civil lawsuits filed by non-US citizens for violations of the "law of nations". By declining to hear Pfizer's appeal and entertain its argument that it cannot be sued in an American court for these claims the Supreme Court has allowed the matter to move forward to trial.
Hydroxyurea, a new drug, does not seem to be effective in reducing the risk of recurrent stroke in children with sickle cell anemia and iron overload.
The National Heart, Lung, and Blood Institute (NHLBI), US, said it was giving up a major trial as there was no evidence that the drug could be any better than the existing treatment.
Government-funded researchers tested AIDS drugs on hundreds of foster children over the past two decades, often without providing them a basic protection afforded in federal law and required by some states, an Associated Press review has found.
Is modern medicine actually "scientific"? The gold standard for modern medicine is the double-blind and placebo-controlled trial. But there are serious problems with these studies, unknown to most, but widely acknowledged by researchers.
One speaker introduced his mother. Another thanked his wife and children. And at the closing ceremony of the Psychedelic Science conference in San Jose, the crowd of 1,000 stood up and applauded in appreciation of one another.
U.S. health regulators have warned Pfizer Inc over a series of failures that led to the overdosing of at least 13 children in a clinical trial of its antipsychotic drug Geodon, according to a letter made public on Tuesday.
Patient families are key to supporting researchers in finding the causes and cures for the medical conditions we treat every day at Childrens Hospital of Wisconsin.
Light Sciences Oncology, Inc. (LSO) today announced the treatment of the first patient in an investigator-sponsored Phase 1 pediatric study of its novel light-activated drug Aptocine(TM) (talaporfin sodium) in neurofibromatosis type 1 (NF-1). Investigators at the Neurofibromatosis/Neuro-Oncology Clinic of Children's Hospital of Philadelphia (CHOP) treated a pediatric patient with NF-1 and plexiform neurofibromas (PN) using Aptocine, which is also in late-stage development for solid tumors. The Neurofibromatosis/Neuro-Oncology Clinic is a program providing care and treatment for children with brain tumors and children with NF-1 and severe and/or life-threatening tumors. Michael Fisher, M.D., at CHOP's Division of Oncology, is the principal investigator of the study.
An experimental drug developed by scientists in China appears to be effective in killing roundworms, a parasite that lurks in the intestines and which affects nearly two billion people in tropical countries.
US drugmaker Pfizer and Nigeria's northern Kano state have clinched a final out-of-court settlement over the 1996 drug trials that led to the deaths of 11 children, lawyers said Monday.